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February 1, 2008 :: New version of ECR Browser

We are happy to announce the release of a completely redesigned version of the ECR Browser tool (dubbed dynamo). Explore and enjoy!

New features:
  - multiple gene annotation tracks
  - possibility to submit your own custom genome annotation
  - share your cussom annotation by submitting it to
       the ECR Browser User Annotation Database
  - enhanced search through RefSeq, UCSC, Ensembl, mRNA, STS, SNPs, etc.
  - zoom in/out using mouse wheel (similar to Google Maps)
  - drag & drop rearrangement of gene annotation tracks
  - drag & drop recentering of the conservation plot
  - gene annotation drop on the conservation plot changes the reference annotation
  - new alignments with repetitive elements included (colored in green)
  - synteny annotation under each conservation track
  - on-the-fly ECR and gene annotation
  - single mouse-click Grab ECR function
  - keyboard shortcuts:
o - zoom out 3x,  i - zoom in 3x,  > - shift to the right,  < - shift to the left,  l - flip the plot,  g - genome selection window,  p - parameters window,  c - highlight coreECRs,  r - reset parameters to defaults,  f - refresh the page,  a - additional alignments,  m - main gene annotation,  z - blastz-based genome alignment

Note: ECR Browser was tested on Internet Explorer 7 and Mozilla Firefox 2. It will probably not work on either Safari or Opera. Please update your Internet browser, if you experience unexpected behavior of ECR Browser.

Previous version: Previous version (dubbed snail) will be kept alive for a couple of months. It will be retired after that.
base genome feature or position (chrN:from-to)  
Genome Alignment
in ECR Browser
Align your sequence to a genome



  Add ECR Browser search button to your Google Toolbar.
Click HERE and select your favorite genome.
(You might need Administrative priviledges to complete the installation.)




Info
  • Details of the alignment strategy and ECR Browser structure.
  • Instructutions on how to use the ECR Browser.

    The ECR Browser is a dynamic whole-genome navigation tool for visualizing and studying evolutionary relationships between vertebrate and non-vertebrate genomes.

    Evolutionary Conserved Regions (ECRs) that have been mapped within alignments of the genomes are presented in this graphical browser, which depicts and color-codes ECRs in relation to known genes that have been annotated in the base genome.

    Please note: Not all alignments are visible by default. Click "Settings" to see all available alignments


Citing ECR Browser
    I. Ovcharenko, M.A. Nobrega, G.G. Loots, and L. Stubbs, Nucleic Acids Research, 32, W280-W286 (2004) [PDF]